Glymphatic clearance function in patients with cerebral small vessel disease
نویسندگان
چکیده
منابع مشابه
Sublingual microvascular changes in patients with cerebral small vessel disease.
BACKGROUND AND PURPOSE It is unknown whether changes in cerebral small vessel disease (SVD) are limited to the brain or part of a generalized vascular disorder. METHODS We examined the sublingual microcirculation of 10 healthy controls, 10 patients with large vessel disease, and 8 with SVD, with side-stream dark field imaging. We analyzed 146 video fragments masked to the origin of the videos...
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BACKGROUND Thrombolytic treatment is of proven benefit in acute ischemic stroke. The term cerebral small vessel disease (SVD) refers to a group of pathological processes affecting the small arteries, arterioles, venules and capillaries of the brain, and encompasses both ischemic and hemorrhagic lesions. Lacunar stroke, an expression of SVD, is associated with an unfavorable long-term prognosis ...
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BACKGROUND Cerebral small vessel disease is a common cause of cognitive impairment and vascular dementia. The cognitive deficit differs from that in Alzheimer's disease, with greater executive/attentional dysfunction and relatively intact episodic memory. OBJECTIVE To develop brief assessment tools that are better adapted to the neuropsychological profile of cerebral small vessel disease. M...
متن کاملCerebral small vessel disease and kidney function predict long-term survival in patients with acute stroke.
BACKGROUND AND PURPOSE Cerebral small vessel disease reflected by white matter lesions (WMLs) in MRI and kidney function reflected by estimated glomerular filtration rate (eGFR) is closely associated in patients without stroke. We studied whether eGFR and WMLs predict long-term survival in patients with acute stroke. METHODS After exclusion of patients with low eGFR (N=5 [1.3%]; <30 mL/min/1....
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BACKGROUND AND PURPOSE Poor kidney function, as measured by glomerular filtration rate (GFR), is closely associated with presence of glomerular small vessel disease. Given the hemodynamic similarities between the vascular beds of the kidney and the brain, we hypothesized an association between kidney function and markers of cerebral small vessel disease on MRI. We investigated this association ...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2021
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2021.118257